Safety and Efficacy of Lipogems Method for Osteoarthritic Knees

Dozens of articles are published annually in the USA discussing the remarkable results of Lipogems. The authors of these publications are surgeons who have often been personally trained by Prof. Tremolada in the use of Lipogems technology, which he invented and patented.

A notable example is this article by physicians Jay Panchal, Gerard Malanga, and Mitchell Sheinkop, published in the American Journal of Orthopedics and featured in several authoritative online publications. Here is a brief excerpt:

Key Study Concepts

Knee osteoarthritis is a chronic condition affecting all races, genders, and ages, but predominantly presents in overweight and elderly individuals. Globally, arthritis is considered the fourth leading cause of disability. In both developing and developed countries, knee osteoarthritis can cause significant quality of life decline in individuals over 65 years due to pain and disability. Conservative, non-surgical treatments can be successful in patients with mild to moderate arthritic pain.

Lipogems Mechanism of Action in Osteoarthritic Knees

The FDA-approved Lipogems device is used to harvest adipose tissue, cleanse it of blood and oil components, and micro-fracture it while maintaining the intact vasculo-stromal niche containing pericytes. This study aimed to evaluate the safety and efficacy of minimally manipulated, micro-fractured autologous adipose tissue in patients with severe refractory knee osteoarthritis.

Conclusions

The injection of minimally manipulated, micro-fractured autologous adipose tissue represents a safe and effective treatment option for patients with severe refractory osteoarthritis (grade 3 or 4) of the knee. This study demonstrated significant improvements in pain, quality of life, and functionality for at least 12 months in the study cohort. Lipogems intervention may represent a non-surgical treatment option to avoid knee joint replacement in this population.

Prof. Tremolada's Commentary

"Lipogems is a method now used in over 20 countries with a growing success history of over 36,000 cases. To make its function comprehensible to everyone, I will simply say that it is currently the best technique used for adipose tissue transplantation."