Lipogems®: The Regenerative Treatment That Rejuvenates Skin

From Vanity Fair Italy Article

Vanity Fair Italy recently published an in-depth look at Lipogems®, presenting it as the most effective method for skin reverse aging. This treatment, developed by Dr. Carlo Tremolada, represents one of the most advanced solutions in the field of aesthetic regenerative medicine.

What is Lipogems®

Lipogems® is a patented methodology approved by the FDA that leverages the principles of regenerative medicine. Initially developed to accelerate healing processes and recovery from sports injuries (also used by skier Sofia Goggia), it finds application in orthopedics for problems such as arthritis and tendonitis, and more recently in aesthetics for skin rejuvenation.

The treatment is based on the body's self-healing principle, using the person's own adipose cells, particularly rich in stem cells, to activate regeneration in tissues where biological functions have slowed down.

The Scientific Principle

According to Dr. Tremolada, Lipogems® involves the grafting of active adult mesenchymal stem cells taken from the patient's fat. These cells, fundamental in the body's repair processes, are extracted through a patented device that reduces the size of adipose tissue without destroying its structure.

The processed adipose tissue is rich in microvessels and pericytes (precursors of mesenchymal stem cells), which are then injected into areas where tissue regeneration needs to be reactivated.

The Treatment Process

The process begins with the extraction of adipose tissue that is processed with a specific device. This tissue, initially shaped like a "ripe raspberry," is progressively reduced through sharp filters that act as a sieve. The reduction occurs with the emission of high pressure, without air, protecting the tissue and keeping its biological information intact.

Inside the device, beads create a water-oil emulsion that is then eliminated, removing all inflammatory factors and leaving the adipose cells biologically activated. The resulting material is then injected where needed, allowing the pericytes to detach and establish themselves in the tissue, becoming active mesenchymal stem cells.

Anti-Aging Effects

In the aesthetic context, Lipogems® works by enhancing microcirculation, counteracting one of the main causes of skin aging. Once grafted, pericytes transform into mesenchymal stem cells that act as "Medicinal Signaling Cells," secreting substances that stimulate the body's self-repair.

These signals regulate the immune system, reduce chronic inflammation, and stimulate other cells to regenerate tissues. The immediate effect is visibly improved skin, thanks to the immunomodulatory action that reduces inflammation. Complete results manifest over nine months.

Practical Applications

Lipogems® can be a partial alternative to surgical lifting, as it improves skin elasticity. However, for significant age-related sagging, it might need to be combined with traditional cosmetic surgery, with the advantage of healthier tissues and faster recovery.

The treatment is suitable for all ages, even as prevention, and has no contraindications for conditions such as vitiligo or psoriasis. It can be performed even in summer or sunny environments, as it increases the skin's resistance to the sun.

Although a single treatment may be sufficient for life, many patients prefer to repeat it after about four years to maintain optimal results.

Source: Vanity Fair Italia, 21. August 2024