Exosomes

Bioactivation with exosomes is a cosmetic-scientific treatment that combines new-generation bioactive principles with microneedling technology. It works by enhancing the skin’s luminosity, firmness, and texture, with no downtime. It is ideal for those seeking a more vital, even, and receptive skin, perfectly prepared to optimize the results of aesthetic medicine treatments.

Treatment Overview

Appropriate for

Recommended for those who wish to improve the quality, brightness, and firmness of the skin on the face, neck, or décolleté, either as a preparatory step or as maintenance for aesthetic medical protocols.

Age

From 25 years and up

Procedure Details

Each session lasts approximately 30–40 minutes

Sessions and frequency

Each session lasts approximately 30–40 minutes

Precautions

None specific; avoid sun exposure and always use broad-spectrum photoprotection after treatment.

Plan Your Treatment

Schedule a video consultation or a call from the clinic

About the Treatment

What are exosomes and how do they act on the skin

Exosomes are microscopic vesicles inspired by the body’s natural mechanisms of cellular communication.
In new-generation formulations, bio-exosomes and biotechnological complexes are used to help stimulate skin functions, improving tone, hydration, and overall appearance.
They represent an evolution in advanced cosmetology, with visible results in brightness and firmness.
Like biological messengers, they carry messenger RNA, microRNA, proteins, enzymes, and bioactive lipids that influence the behavior of recipient cells.

Facial treatment with exosomes: who is it for

The facial treatment with exosomes is ideal for dull, dry, or stressed skin in need of a revitalizing boost.
It is recommended for those who wish to:

  • Increase facial brightness and smoothness
  • Improve skin texture and minimize enlarged pores
  • Enhance the results of fillers, lasers, or biostimulation treatments
  • Maintain long-term skin quality

Plant exosomes and biotechnological complexes

The new formulations used in Image protocols contain plant-derived exosomes, peptides, and skin-supporting factors.
These latest-generation ingredients act gently and progressively, improving the skin’s barrier function, hydration, and resilience.
The treatment can also be performed on the neck and décolleté to achieve a globally even and luminous appearance.

Microneedling with exosomes: technology that strengthens the skin

Microneedling with exosomes uses a professional micro-needle device (dermapen) that creates controlled micro-channels in the skin, stimulating natural cellular turnover and enhancing the penetration of active ingredients.
Each session lasts about 30–40 minutes and requires no recovery time.
Immediately after treatment, the skin appears more radiant, smooth, and compact.

Exosomes for the scalp: vitality and strength for the hair

Exosome-based technology can also be applied to scalp protocols, combined with gentle microneedling.
This treatment helps improve microcirculation and follicular quality, promoting healthier, more vital-looking hair.

Why commercial exosomes are not real exosomes

In aesthetic medicine, the term exosome is often misused.
The products currently available on the market do not contain true biological exosomes — the natural vesicles released by living cells — but rather bio-derived or biotechnological complexes inspired by their mechanisms of communication.
They are therefore cosmetic-functional formulations effective as skin boosters, but devoid of the cellular activity typical of authentic autologous exosomes, such as those naturally produced in medical treatments like Lipogems®.

➤ Lipogems® (Microfragmented adipose tissue)

Adipose tissue contains mesenchymal stromal cells (MSC) and vital pericytes.
During the Lipogems treatment, these cells remain intact and metabolically active, releasing exosomes and paracrine factors that:

  • Reduce inflammation
  • Promote neovascularization
  • Stimulate tissue regeneration

These exosomes are biologically active, traceable, and fully compatible with the patient’s own body.

Plan Your Treatment

Schedule a video consultation or a call from the clinic

Frequently Asked Questions

What is Exosome Bioactivation?

It is a next-generation aesthetic treatment that combines formulations based on bio-exosomes with microneedling to improve the skin’s radiance, hydration, and firmness.

What is the role of Microneedling in the Exosome treatment?

Microneedling enhances the penetration of active ingredients and stimulates skin microcirculation, amplifying the effectiveness of the treatment and improving skin texture.

How many sessions are needed to see results?

A cycle of 3–5 sessions spaced 2–4 weeks apart is recommended. Improvements in skin brightness and tone are often visible after the very first applications.

Why are autologous exosomes more effective?

Because they speak the body’s own biological “language.”
Produced by the patient’s own cells, they are perfectly recognized by the receiving tissues and activate regeneration processes that are coherent, long-lasting, and free of immunological or infectious risks.

Are all exosome treatments the same?

No. There is a fundamental difference between autologous exosomes, naturally produced by the body (as in Lipogems®), and commercial products marketed as “exosome-based,” which derive from external cell cultures. Only the former are biologically compatible, safe, and scientifically validated.

Want More Info?

If you need more information feel free to give us a call on: +39 02 76280736 or contact us using the form below.

Attention

The information available on the website istitutoimage.it is intended solely for informational purposes and is in no way a substitute for specialist medical advice. The contents are drafted in compliance with Art. 56 of the FNOMCeO Code of Ethics and the Ministerial Circular dated 18/12/2024. The information published has been prepared by qualified doctors and surgeons and is solely for educational purposes:

  • it does not in any way constitute a diagnosis;
  • it does not replace the direct doctor-patient relationship;
  • it must not be used as a prescription for treatments or as a basis for autonomous therapeutic decisions.

To assess suitability for aesthetic medicine treatments or plastic surgery procedures, a specialist medical consultation is always required.

For any questions, the Image Regenerative Clinic team is available with no obligation. Read the full Disclaimer.

Mission

This website is aimed at users seeking qualified and up-to-date information about regenerative aesthetic medicine, plastic surgery and longevity programs. Its contents are intended to provide general knowledge and are not a substitute for the doctor-patient relationship. Image Regenerative Clinic is committed to offering scientifically supported treatments and therapies with the utmost transparency and in full compliance with current regulations.

Website Authors

Dr. Carlo Tremolada – OMCEO Milan registration no. 30098  All the contents and images on this website have been written, reviewed and approved by the internal Medical-Scientific Committee coordinated by Dr. Carlo Tremolada, in compliance with Art. 56 of the FNOMCeO Code of Ethics and current regulations on healthcare advertising.

Website Ownership

The website istitutoimage.it is owned by Image Regenerative Clinic S.r.l.

It does not contain banner advertising, does not host sponsored content and does not benefit from grants or revenue from external advertising.